Two University of Galway projects win ERC Proof of Concept grants
Research projects from University of Galway on 3-D printing and pain relief are among 136 to receive European Research Council (ERC) Proof of Concept grants.
The projects are the only two from Ireland to be supported in the current round.
The 3D printing project is led by Prof Ted Vaughan, Director of the Institute for Health Discovery and Innovation and Professor of Biomedical Engineering, alongside Dr Mahtab Vafaeefar, Postdoctoral Researcher in Biomedical Engineering at University of Galway.
The new technology offers unprecedented freedom to create complex and lightweight parts as many products are still designed using approaches developed for traditional manufacturing, limiting performance and increasing material waste.
The team will address this gap by developing a new, easy-to-use design approach that brings design and production considerations together in one simple process, helping engineers move quickly from an idea to a part that is ready to print and use in the real world.
Prof Vaughan said: “Too often, we simply ‘print’ conventional designs rather than truly exploiting the capabilities of additive manufacturing. Our goal is to provide intuitive tools that automatically generate high-performance, production-ready designs that are truly functionally tailored to each application, reducing costs, saving material and accelerating innovation.”
The software builds on biomimetic principles derived from models developed during Professor Vaughan’s European Research Council Starting Grant, taking inspiration from how nature designs complex structure and translating these insights into industry-ready design tools that will enable lightweight, efficient, and high-performance components across a range of engineering applications.
The second project, Uro-Lieve, a minimally invasive, biodegradable capsaicin hydrogel designed to selectively silence pain fibres as a therapy for relief from symptoms of painful bladder syndrome, known as interstitial cystitis. The new approach avoids the severe burning of current treatments.
The project is led by Prof Martin O’ Halloran, principal investigator in the College of Medicine Nursing and Health Sciences and Executive Director of the BioInnovate Programme at University of Galway.
Prof O’ Halloran said: “Painful bladder syndrome (interstitial cystitis) is a chronic, underdiagnosed condition marked by persistent bladder pain, urgency, and frequency, with profound impacts on quality of life, mental health, and economic productivity. This proposal introduces Uro-Lieve, a minimally invasive, biodegradable capsaicin hydrogel designed to selectively silence pain fibres while avoiding the severe burning of current treatments. It highlights a major unmet clinical need and the broader structural neglect of women’s pain in research and healthcare.”
The European Research Council Proof of Concept scheme is funded under Horizon Europe, the EU’s framework programme for research and innovation. It provides grants to existing ERC grant holders to bridge the gap between pioneering research and early-stage commercial or societal application.
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